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For example, a soluble form of an immune checkpoint protein ligand (e.g., a stabilized extracellular domain) can bind to its receptor to indirectly reduce the effective concentration of receptor binding to the appropriate ligand

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BBA-Mol Cell Biol L 1851(4):308–330 [DOI] [PMC free article] [PubMed] [Google Scholar] Kulkarni PG, Mohire VM, Waghmare PP, Banerjee T (2024) Interplay of mitochondria associated membrane proteins and autophagy: Implications in neurodegeneration